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Improving the number of serotonin diminishes the feelings of hysteria, uneasyness, loss of appetite, anxiety, and depressive disorders that often accompany lower numbers of the hormone serotonin. St. st. John's Wort side effects has become repeatedly compared to certain SSRIs like Zoloft along with Prozac and shown very similar results without lots of the unfavorable side affects that happen to be associated with these prescription drugs or the high price tags which go together with all of them.